What is Capstar?

Capstar for dogs is an oral tablet that contains 11.4 or 57.0 of nitenpyram, a chemical that kills adult fleas. It may also be given to puppies, cats and kittens that are 4 weeks of age or older and weigh 2 pounds or greater. It is not for human use and is strictly for animal use only.

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Tablet of Contents
Does Capstar kill ticks
Where can I buy Capstar locally?
Where can I buy Capstar for cats?
Capstar side effects
Capstar Main Ingredients

Nitenpyram, the active ingredient of Capstar for dogs, works as a neurotoxin by blocking neural messages and binding tightly to the central nervous system of the insect. This would cause rapid death to the flea, and protection for your pet.

Capstar for dogs is rapid acting. It takes effect within 30 minutes after administration to the animal. A single dose of this medicine should be able to kill the adult flea on your pet. If your pet gets re-infested, it is safe to give another dose as often as once a day.

Fleas reproduce very fast. A single female flea can produce up to 2,000 eggs in her lifetime. These eggs hatch and mature into adults in over three weeks. The female flea feeds by ingesting blood from your pet and eventually lays her eggs on your pet’s skin. The eggs hatch and can live undetected in your pet’s surroundings such as in carpets and beddings. The flea larvae will spin into a cocoon and then the young flea will emerge from it, and then goes onto your pet. Then the life cycle of the flea continues.

The flea infestation on your pet can cause irritations and other skin conditions such as flea allergy dermatitis (FAD) in dogs and military dermatitis for cats. Fleas may also be carriers of parasites like tapeworms and transmit them onto your pets.

Capstar manufacturer is Novartis Animal Health US, Inc. in Greensboro, NC.

Does Capstar kill ticks?

Capstar for dogs cannot be used against ticks. Ticks are carriers for causative microorganism of Lyme disease. Capstar for dogs is indicated for the use against fleas.

Where can I buy Capstar locally?

Capstar may be purchased locally at Petco, Petsmart, Walmart, Target, and Walgreens. It may also be bought online at Amazon and eBay and websites of the stores mentioned earlier. You can use capstar coupons to avail of the promos offered by the manufacturer.

Where can I buy Capstar for cats?

Capstar for cats may be purchased at Petco, Petsmart, Target, and Walmart. It may also be bought online at Amazon and eBay and websites of the stores mentioned earlier.

Capstar side effects

The following are the adverse effects reported with Capstar for dogs:

  • hyperactivity,
  • panting,
  • fever,
  • nervousness,
  • vocalization,
  • increased heart rate,
  • gastrointestinal effects (vomiting, diarrhea, decreased appetite, salivation) and
  • neurological effects (seizures, trembling, pupil dilation, difficulty breathing).

Information sheets for Capstar for dogs say that the medicine is “safe for pregnant and nursing dogs and cats”. However, reports have shown birth defects and loss of unborn puppies and kittens following administration of Capstar to pregnant animals. Also, reports of newborn puppies and kittens’ deaths were shown following the administration of Capstar medication in lactating animals. These effects may not be guaranteed to be caused by the product, therefore the manufacturer strongly recommends to be cautious when giving the medicine to pregnant and lactating animals.

Capstar Main Ingredients

Capstar tablets contains 11.4 or 57.0 mg of Nitenpyram, a chemical that belongs to the class of neonicotinoids, which is responsible for killing adult fleas. This chemical acts a neurotoxin on the nicotinic acetyl choline receptors in the insect’s nervous system. These receptors serve as binding sites for endogenous nicotinic acetyl choline, a neurotransmitter that activates the sympathetic and parasympathetic nerves of the insect, stimulating the insect’s muscles, and consequently causing severe muscle contraction thus paralyzing the insect and then killing it.
Nitenpyram is structurally similar with acetyl choline, thus it produces similar effects. Nitenpyram produces nicotine poisoning on the insect through overstimulation of the receptors thus causing rigidity and eventually death. Nitenpyram is highly specific for the nicotinic acetyl choline receptors of the nervous system of insects like fleas and does not affect the animal concerned.


Capstar is used for the treatment of flea infestations on dogs and cats. It causes extreme paralysis on the insect thus killing it. However, you have to give this medicine once a day to your dog or cat if the fleas are still infecting your house. Compared to other flea products on the market this is the least effective, though with different dogs – every reaction is different. The Editors choice recommends Comfortis for dog. However, if you still choose to purchase Capstar check out the link below to get it delivered to your dog fast.


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